HTA Publication - The opportunities and challenges of pragmatic point-of-care randomised trials using routinely collected electronic records: evaluations of two exemplar trials

The Health Technology Assessment Journal have just published the report of research commissioned that looked at the opportunities and challenges of point of care randomised trials using routinely collected electronic health records (EHR) in GP surgeries.

The research concluded that EHR point-of-care trials are feasible, although the recruitment of clinicians is a major challenge owing to the complexity of trial approvals. These trials will provide substantial evidence on clinical effectiveness only if trial interventions and participating clinicians and patients are typical of usual clinical care and trials are simple to initiate and conduct. Recommendations for research include the development of evidence and implementation of risk proportionality in trial governance and conduct.

The paper can be accessed at: http://www.journalslibrary.nihr.ac.uk/__data/assets/pdf_file/0006/121596...